Chronic Constipation Linked to Cognitive Decline

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Chronic Constipation Linked to Cognitive Decline

Chronic constipation may be associated with worsening cognitive function, new data from three prospective cohort studies with more than 100,000 adults show.

Compared to individuals who have a bowel movement once daily, adults with constipation who have a bowel movement every 3 days or more had significantly worse cognition that was commensurate with an additional 3 years of chronologic cognitive aging, the investigators found.

“We should watch for symptoms of abnormal intestinal function, especially constipation, in older individuals, as these symptoms may hint at a higher risk of cognitive decline in the future,” study investigator Chaoran Ma, MD, PhD, former research fellow at Brigham and Women’s Hospital and Harvard Medical School and current assistant professor at the University of Massachusetts Amherst, told Medscape Medical News.

The findings were presented at the Alzheimer’s Association International Conference (AAIC) 2023.

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