Recently, scientists have brought more uses of the drug to light. Physicians prescribe metformin to help treat polycystic ovary syndrome, and some researchers have suggested that the drug may improve fertility and help regulate menstrual cycles.
Some have even suggested that metformin may improve longevity. Animal studies have found that the drug may influence the metabolic processes associated with aging and age-related conditions, and clinical trials of metformin’s effects on human lifespan are currently under way.
Around 2 years ago, researchers from the Biozentrum at the University of Basel in Switzerland found that metformin, in combination with a blood pressure drug, can stop cancer tumors from growing.
In new research, scientists now show how this drug cocktail works: the combination of metformin and the antihypertensive syrosingopine cuts off cancer’s energy supply, resulting in the death of cancer cells.
The new study was conducted at Biozentrum in collaboration with Basilea Pharmaceutica International Ltd. Don Benjamin, from Biozentrum, is the first author of the study.