Genetics Not Environment for Autism Risk
Nearly 60% of the risk for autism is genetic, and most of that risk is due to inherited gene variants that are common in the population, a large Swedish study shows.
“We show very clearly that inherited common variants comprise the bulk of the risk that sets up susceptibility to autism,” lead investigator Joseph D. Buxbaum, PhD, director of the Seaver Autism Center for Research and Treatment, Icahn School of Medicine at Mount Sinai in New York City, said in a statement.
“But while families can be genetically loaded for autism risk, it may take additional rare genetic factors to actually produce the disorder in a particular family member,” he added.
The Population-Based Autism Genetics and Environment Study (PAGES) was published online July 20 in Nature Genetics.
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