Herpes Simplex May Double Alzheimer’s Risk

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Herpes Simplex May Double Alzheimer’s Risk


Herpes simplex virus infection appears to double the risk of developing Alzheimer’s disease (AD), claim Swedish researchers in two separate studies.


In a nested case-control study, Hugo Lövheim, MD, PhD, from Umeå University, in Sweden, and colleagues found that the risk for AD was significantly associated with prior herpes simplex virus type 1 (HSV1) infection.

Furthermore, a second investigation by the same team using data from an ongoing prospective cohort study indicated that reactivated HSV1 infection increased the risk for AD two-fold, although the association with the presence of HSV infection was not significant.
Both studies are published in the journal Alzheimer’s and Dementia.

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