Metformin and Insulin Combo Cuts Mortality in Type 2 Diabetes

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Metformin and Insulin Combo Cuts Mortality in Type 2 Diabetes

A new retrospective study indicates that, in type 2 diabetes, treatment with insulin is safer when it is used together with metformin.
In the research, recently published in PLoS One, a team from Cardiff University, Wales, showed that patients on insulin and metformin were at a significant 40% reduced risk for death and a significant 25% reduced risk for major adverse cardiac events (MACE) compared with those treated with only insulin. However, the combination was not significant in reducing cancer.
“If at all possible, patients with type 2 diabetes initiated on insulin should also be given metformin,” senior author Craig Currie, PhD, professor of applied pharmacoepidemiology, Cardiff University, Wales, told Medscape Medical News.
PLoS One. Published online May 6, 2016. Article

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