Risks to Heart and Blood Pressure in Young Adults = Midlife Cognitive Decline
Beginning in young adulthood, exposure over 25 years to high blood pressure, high fasting blood glucose levels, and, to some extent, elevated cholesterol has a negative effect on cognition by midlife, a new study suggests.
The study showed that even at subclinical levels, the cumulative effects of cardiovascular risk factors (CVRFs) are eventually associated with worse cognitive function.
Adults under age 30 years with such risk factors may be a “critical target group” for early intervention, said the authors.
“The fact that we even saw something was kind of remarkable because this is a pretty young group,” lead author Kristine Yaffe, MD, professor, psychiatry and neurology, University of California at San Francisco, told Medscape Medical News.
“The differences weren’t huge; we’re not saying this is Alzheimer’s or pre-Alzheimer’s, but these risk factors seem to matter in young to middle age. One of the questions is, is this the beginning of something clinical down the road?”
The study was published online March 31 in Circulation.
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