Statins associated with 46% rise in type 2 diabetes risk

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Statins associated with 46% rise in type 2 diabetes risk

Statins can lower cholesterol and even lower inflammation to keep the risk of heart disease down, but these commonly prescribed drugs may increase the risk of diabetes, and by a considerable amount


This suggests a higher risk for diabetes with statins in the general population than has previously been reported, which has been in the region of a 10% to 22% increased risk, report the researchers, led by Henna Cederberg, MD, PhD, from the University of Eastern Finland and Kuopio University Hospital, and colleagues, who published their study online March 4 in Diabetologia.


The link between statin use and higher risk of diabetes is not new. Back in 2013, for example, Medical News Today reported on a study published in The BMJ that found certain statins – particularly atorvastatin (Lipitor), rosuvastatin (Crestor) and simvastatin (Zocor) – raised the risk of diabetes by up to 22%.

In the study published in Diabetologia, scientists from Finland found that men prescribed statins to lower their cholesterol had a 46% greater chance of developing diabetes after six years compared to those who weren’t taking the drug. What’s more, the statins seemed to make people more resistant to the effects of insulin—which breaks down sugar—and to secrete less insulin. The impact on insulin seemed to be greatest among those who started out with the lowest, and closest to normal, levels of blood glucose. And the higher the dose of the statin, and the longer the patients took them, the greater their risk of diabetes.


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