Vitamin D Deficiency Predicts Cognitive Decline

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Vitamin D Deficiency Predicts Cognitive Decline

A new study supports a link between low levels of vitamin D and increased risk for cognitive decline, prompting calls for clinical trials to test whether vitamin D supplementation may delay or prevent dementia.

In a group of cognitively intact older adults, serum 25-hydroxyvitamin D (25OHD) levels below 75 nmol/L at the outset predicted cognitive decline over roughly the next 4 years, independent of other factors.

“[N]eurologists and geriatricians should be aware of the possibility that in elderly individuals, vitamin D supplementation might be a potential cost-effective strategy for preventing neurodegenerative diseases,” Elena D. Toffanello, MD, from University of Padova, Italy, and colleagues say.

Their study was published online November 5 in Neurology.

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