Improving deep sleep may prevent dementia, study finds

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Improving deep sleep may prevent dementia, study finds

As little as 1% reduction in deep sleep per year for people over 60 years of age translates into a 27% increased risk of dementia, according to a study which suggests that enhancing or maintaining deep sleep, also known as slow wave sleep, in older years could stave off dementia.

Even adjusting for age, sex, cohort, , smoking status, sleeping medication use, antidepressant use, and anxiolytic use, each percentage decrease in deep sleep each year was associated with a 27% increase in the risk of dementia.

“We used these to examine how slow-wave sleep changed with aging and whether changes in slow-wave sleep percentage were associated with the risk of later-life dementia up to 17 years later,” he said.

“We also examined whether genetic risk for Alzheimer’s Disease or brain volumes suggestive of early neurodegeneration were associated with a reduction in . We found that a genetic risk factor for Alzheimer’s disease, but not brain volume, was associated with accelerated declines in slow wave sleep.”

More information: Jayandra J. Himali et al, Association Between Slow-Wave Sleep Loss and Incident Dementia, JAMA Neurology (2023). DOI: 10.1001/jamaneurol.2023.3889

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