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Improving deep sleep may prevent dementia, study finds
As little as 1% reduction in deep sleep per year for people over 60 years of age translates into a 27% increased risk of dementia, according to a study which suggests that enhancing or maintaining deep sleep, also known as slow wave sleep, in older years could stave off dementia.
Even adjusting for age, sex, cohort, genetic factors, smoking status, sleeping medication use, antidepressant use, and anxiolytic use, each percentage decrease in deep sleep each year was associated with a 27% increase in the risk of dementia.
“We used these to examine how slow-wave sleep changed with aging and whether changes in slow-wave sleep percentage were associated with the risk of later-life dementia up to 17 years later,” he said.
“We also examined whether genetic risk for Alzheimer’s Disease or brain volumes suggestive of early neurodegeneration were associated with a reduction in slow-wave sleep. We found that a genetic risk factor for Alzheimer’s disease, but not brain volume, was associated with accelerated declines in slow wave sleep.”
More information: Jayandra J. Himali et al, Association Between Slow-Wave Sleep Loss and Incident Dementia, JAMA Neurology (2023). DOI: 10.1001/jamaneurol.2023.3889
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