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Two Diets Tied to Lower Alzheimer’s Pathology at Autopsy
A novel study provides strong evidence supporting the adoption of a healthy diet to protect the aging brain.
In a cohort of deceased older adults, those who had adhered to the Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) and Mediterranean diets for nearly a decade before death had less global Alzheimer’s disease (AD)–related pathology, primarily less beta-amyloid, at autopsy.
Those who most closely followed these diets had almost 40% lower odds of having an AD diagnosis at death. The findings offer one mechanism by which healthy diets protect cognition.
“While our research doesn’t prove that a healthy diet resulted in fewer brain deposits of amyloid plaques…we know there is a relationship, and following the MIND and Mediterranean diets may be one way that people can improve their brain health and protect cognition as they age,” study investigator Puja Agarwal, PhD, of RUSH University Medical Center in Chicago, said in a statement.
“Our finding that eating more green leafy vegetables is in itself associated with fewer signs of Alzheimer’s disease in the brain is intriguing enough for people to consider adding more of these vegetables to their diet,” Agarwal said in the news release.
As previously reported by Medscape Medical News, data from the MAP cohort showed that adherence to the MIND diet can improve memory and thinking skills of older adults, even in the presence of AD pathology,
The study was published online March 8 in Neurology.
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