Phthalates Linked to Testosterone Reductions in Both Men and Women

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Phthalates Linked to Testosterone Reductions in Both Men and Women

Increased urinary levels of endocrine-disrupting phthalates, found in flexible plastic and some personal-care products, are associated with significant declines in testosterone levels not just in men, but in women and children as well, according to research published online August 14 in the Journal of Clinical Endocrinology & Metabolism.

“We found associations between markers of phthalate exposure and testosterone levels among multiple age groups and in both sexes, including children — 6- to 12-year-old boys and girls, and girls ages 12 to 20,” lead author John D. Meeker, ScD, CIH, told Medscape Medical News.

The findings add to mounting evidence on reproductive risks linked to exposure to the endocrine-disrupting chemicals; however, many questions have remained regarding which chemicals are disruptive and who is most at risk. Dr. Meeker admits that while their findings expand the body of research in this field, the clinical implications remain unclear.

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