Healthy Gut Tied to Better Cognition

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Healthy Gut Tied to Better Cognition

A healthy, diverse gut microbiome is associated with better cognitive function in middle age, new research suggests.

Investigators conducted cognitive testing and analyzed stool samples in close to 600 adults and found that beta-diversity, which is a between-person measure of gut microbial community composition, was significantly associated with cognitive scores.

Three specific bacterial genera showed a positive association with performance on at least one cognitive test, while one showed a negative association.

“Data from our study support an association between the gut microbial community and measure of cognitive function — results that are consistent with findings from other human and animal research,” study investigator Katie Meyer, ScD, assistant professor, Department of Nutrition, UNC Gillings School of Public Health, Chapel Hill, North Carolina, told Medscape Medical News.

“However, it is also important to recognize that we are still learning about how to characterize the role of this dynamic ecological community and delineate mechanistic pathways,” she said.

The study was published online February 9 in JAMA Network Open.

JAMA Netw Open. Published online February 8, 2022. Full text

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