Obesity Poses Much Bigger Risk for Diabetes Than Bad Genes

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Obesity Poses Much Bigger Risk for Diabetes Than Bad Genes


 Obesity is by far the greatest risk factor for developing type 2 diabetes, more than either having a genetic predisposition to diabetes or poor health habits, according to a large case-control study from Denmark.  
Specifically, among people who were mainly in their late 50s, the likelihood of developing type 2 diabetes during the next decade or so was sixfold higher if they were obese than if they were a normal weight — much greater than the risk from a poor lifestyle (related to smoking, drinking, poor diet, not exercising) or genetic predisposition.
Importantly, the study showed “individuals with an unfavorable lifestyle and obesity are at greater risk of incident type 2 diabetes regardless of their genetic risk,” Hermina Jakupović, PhD fellow, MSc, Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Denmark, told Medscape Medical News.
Jakupović will present the findings in a poster here at the European Association for the Study of Diabetes (EASD) 2019 Annual Meeting.

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