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GLP-1 Drugs Again Linked to Blindness Risk
People with type 2 diabetes taking GLP-1 medicines may experience potentially blinding eye conditions as soon as the day after starting the drugs, and eye doctors are now asking their patients to be vigilant in speaking up about any vision changes while taking them.
A new study in JAMA Ophthalmology highlights the importance for people with type 2 diabetes who take GLP-1 medicines to contact their health care provider immediately if they experience any vision changes because of the heightened risk for problems such as swelling of the optic nerve, a problem known as an “eye stroke.”
The findings suggest that rapid correction of high blood sugar may be linked to the onset of the new vision problems, the study authors concluded.
The new research summarized vision problems of nine people with type 2 diabetes taking either semaglutide or tirzepatide, which are GLP-1 medicines. Semaglutide is known by the brand names Ozempic and Wegovy, and tirzepatide is known by the brand names Mounjaro and Zepbound.
SOURCES:
JAMA Ophthalmology: “Ophthalmic Complications Associated With the Antidiabetic Drugs Semaglutide and Tirzepatide,” “Author Interview Podcast, Podcast (17:17) Ophthalmic Complications Associated With Semaglutide and Tirzepatide,” “Risk of Nonarteritic Anterior Ischemic Optic Neuropathy in Patients Prescribed Semaglutide.”
University of Utah Health Moran Eye Center: “John A. Moran Eye Center Physician Scientists Keeping an Eye on Patients Taking New Class of Diabetes and Weight Loss Drugs.”
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