Here’s What Happens to People Who Stay on Wegovy Long Term

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Here’s What Happens to People Who Stay on Wegovy Long Term

Results from the longest-running trial of semaglutide—the active ingredient in the popular drugs Ozempic and Wegovy—are in, and the verdict is decidedly positive. The study found that people taking semaglutide tended to maintain their initial weight loss for up to four years. Other trial data presented this week also suggests that semaglutide can improve people’s heart health even without causing weight loss.

Last summer, the makers of semaglutide, Novo Nordisk, reported the main findings of the SELECT trial. The trial involved over 17,000 people and tested whether the drug could help overweight or obese individuals without diabetes but with pre-existing cardiovascular disease. The trial found that high-dose semaglutide cut the risk of major cardiovascular events by 20% for up to five years when compared to a placebo.

The new research, published Monday in Nature Medicine, specifically analyzed the weight loss outcomes of those in the SELECT trial. On average, people taking semaglutide lost about 10% of their baseline weight within 65 weeks, far more than those on placebo, according to the study. By year four, these results remained remarkably consistent, with an average 10.2 percent weight loss seen in patients still taking the drug.

via Blogger https://bit.ly/4bJGwYV