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Intermittent Fasting Promotes Weight Loss, Improves Lipids
Limiting food consumption to a 10-hour window each day promotes weight loss and improves cardiometabolic abnormalities in women with metabolic syndrome, a small pilot study suggests.
“There has been a lot of discussion about intermittent fasting and what time window people should eat within to get the benefits of this kind of diet,” co-corresponding author Satchidananda Panda, PhD, said in a statement.
“Based on what we’ve observed in mice, a 10-hour time window seems to convey these benefits. At the same time, it’s not so restrictive that people can’t follow it long-term,” added Panda, of the Salk Institute for Biological Studies, La Jolla, California. Panda is the author of the book The Circadian Code and collects royalties.
The study was published online December 5 in Cell Metabolism by Michael J. Wilkinson, MD, of the University of California, San Diego, and colleagues.
Because most of the women were taking a statin, antihypertensive medications, or both at study entry, “the observed benefits of time-restricted eating were additive to the effects of these medications…and in this population at high risk for cardiovascular disease, a significant reduction in atherogenic lipids, blood pressure, and blood glucose on top of medical therapy has important clinical implications,” say the investigators.
“The high level of adherence to time-restricted eating in our study, no reported adverse effects, and low dropout rate suggest that a self-selected 10-hour window for time-restricted eating may be feasible for patients with metabolic syndrome to adhere to over a longer period of time,” the investigators conclude.
Cell Metab. Published online December 5, 2019. Abstract
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