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More Evidence Links Gum Disease and Dementia Risk
Periodontal disease is associated with later development of mild cognitive impairment (MCI) or dementia, especially in those with severe gum inflammation and edentulism (tooth loss), new research suggests.
Over a 20-year period, investigators prospectively followed more than 8000 individuals around the age of 63 years who did not have cognitive impairment or dementia at baseline, grouping them based on the extent and severity of their periodontal disease and number of lost teeth.
Results showed that 14% of participants with healthy gums and all their teeth at baseline developed dementia, compared with 18% of those with mild periodontal disease and 22% who had severe periodontal disease. The highest percentage (23%) of participants who developed dementia was found in those who were edentulous (toothless).
After accounting for comorbidities that might affect dementia risk, edentulous participants had a 20% higher risk for developing MCI or dementia compared with the healthy group.
The study was published online July 29 in Neurology.
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