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Psilocybin 6 Times More Effective Than Nicotine Patch to Help Smokers Quit
A Trip To Quit: Quitting smoking is hard. Really hard. Nicotine patches have been a go-to cessation method for decades, but a recent pilot study from Johns Hopkins University has found a surprising alternative that might work better: psilocybin (AKA “magic mushrooms”).
The Study: The researchers randomized 82 psychiatrically healthy adult daily tobacco smokers into two groups. Both groups received 13 weeks of smoking cessation–focused cognitive behavior therapy, but one group wore nicotine patches for eight to 10 weeks and the other took one dose (30 milligrams per 70 kilograms of body weight) of the naturally occurring psychedelic psilocybin. Researchers tracked the participants for six months to see if they stayed smoke-free via self-reported questionnaires, as well as urine tests for nicotine and breath tests for carbon monoxide from cigarette smoke.
The Takeaway: The participants in the psilocybin group were six times more likely to quit — and stay off tobacco for six months — than those in the patch group. Only 10% of the participants in the patch group had the same outcome.
Keep in Mind: More research is needed to see if this therapy can help smokers remain smoke-free for longer, particularly because 75% of former smokers relapse by the six-month mark.
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