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What Happens When You Drink Alcohol on Ozempic
You Should Know: GLP-1 drugs like Ozempic and Wegovy are known for curbing hunger, but researchers are finding they may also blunt the brain’s reward response tied to addictive behaviors. That includes food, nicotine, and alcohol.
Going Deeper: A new study adds an unexpected twist. These drugs don’t only alter desire when it comes to alcohol — they change how the body processes it. When participants taking GLP-1s consumed three drinks under observation, their blood alcohol levels rose more slowly, and they reported feeling less intoxicated overall. The “buzz” arrived later and hit weaker. That means the drugs might reduce both the physiological and psychological reinforcement that fuels drinking behavior.
Takeaway: This dual effect of muted reward plus slower absorption could help explain early reports of reduced alcohol and substance use among GLP-1 users. But it also raises questions about whether people might drink more to “feel something,” potentially offsetting the benefit.
Bottom Line: We’re only beginning to understand how GLP-1s reshape the body’s reward and metabolism systems. They may dampen cravings and the pleasure reward that drives them, but that’s not the same as fixing addiction. More research is needed to confirm the effects.
Going Deeper: A new study adds an unexpected twist. These drugs don’t only alter desire when it comes to alcohol — they change how the body processes it. When participants taking GLP-1s consumed three drinks under observation, their blood alcohol levels rose more slowly, and they reported feeling less intoxicated overall. The “buzz” arrived later and hit weaker. That means the drugs might reduce both the physiological and psychological reinforcement that fuels drinking behavior.
Takeaway: This dual effect of muted reward plus slower absorption could help explain early reports of reduced alcohol and substance use among GLP-1 users. But it also raises questions about whether people might drink more to “feel something,” potentially offsetting the benefit.
Bottom Line: We’re only beginning to understand how GLP-1s reshape the body’s reward and metabolism systems. They may dampen cravings and the pleasure reward that drives them, but that’s not the same as fixing addiction. More research is needed to confirm the effects.
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