Posted by & filed under Uncategorized.

safety-lane.com 07105
chiropractic-lane.com
www.cbd-lane
NEWARK
http://www.healthy-lane.com/

Four-Drug Combo Gets BP Down in One Step: QUARTET-USA

[I can’t stress enough that with so many different hypertensive medications on the market all of which work in small different ways it only makes sense to use more than one, but at low doses to avoid the side-effects that come with large concentrations – Dr. Lane]

Use of a combination antihypertensive product containing quarter doses of four different drugs could be an effective strategy to get patients to target blood pressures in one step, a new study suggests. 

The study, QUARTET-USA, showed a reduction in blood pressure of almost 5 mm Hg more than the comparator of one antihypertensive agent at standard dose over the 12-week follow up period in patients with mild to moderate hypertension.

The QUARTET-USA study was presented at the American Heart Association (AHA) Scientific Sessions 2022 by Mark Huffman, MD, professor of medicine at Washington University School of Medicine, St Louis, Missouri. 

It builds on a previous trial, QUARTET, conducted in Australia, which first showed benefits with this approach.

In the new US study, which was considerably smaller than the Australian trial, the four-drug combination, including candesartan, amlodipine, indapamide, and bisoprolol, led to a -4.8/-4.9 mm Hg greater reduction in blood pressure from baseline to 12 weeks compared with standard-dose candesartan monotherapy.

American Heart Association (AHA) 2022 Scientific Sessions: Presentation 19617. Presented November 6, 2022.  

via Blogger https://bit.ly/3NRjZ1m