Calcium and Vitamin D Boost HRT Effect on Hip Fracture Risk


Calcium and Vitamin D Boost HRT Effect on Hip Fracture Risk

According to new data from the Women’s Health Initiative (WHI), postmenopausal women who took hormone replacement therapy (HRT) had a lower risk for hip fracture than women who received placebo, and they had an even lower risk if they also took calcium and vitamin D. Taking these supplements without HRT, however, did not lower the risk for hip fracture.
The study, by John A. Robbins, MD, from the University of California, Davis, in Sacramento, and colleagues was published online June 26 in Menopause.
“Our further investigation of the WHI data shows that [calcium and vitamin D supplementation] — although, by itself, may not be of statistically proven benefit for fracture prevention — may have a significant effect when used with [hormone therapy],” the authors write. “The current study provides evidence that supplemental [calcium and vitamin D] augments the protective effects of [hormone therapy] against hip fracture, and vice versa.”
Menopause. Published online June 26, 2013. Abstract

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