Chondroitin-Glucosamine Reduced Pain in Knee Arthritis

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Chondroitin-Glucosamine Reduced Pain in Knee Arthritis

A new randomized controlled clinical trial (RCT) has provided some support for the suggestion raised in the 2008 Glucosamine/Chondroitin Arthritis Intervention Trial (GAIT) that glucosamine plus chondroitin sulfate might provide clinically significant pain relief for patients with moderate to severe knee osteoarthritis (OA) pain, despite being ineffective against milder OA pain.

Marc C. Hochberg, MD, from the University of Maryland School of Medicine, Baltimore, and colleagues from France, Germany, Poland, and Spain report in an article published online January 14 in the Annals of the Rheumatic Diseases that a combination glucosamine/chondroitin sulfate product produced a 50.1% decrease in Western Ontario and McMaster OA index (WOMAC) pain, which is comparable to the 50.2% decrease seen in patients randomly assigned to receive celecoxib. Bioibérica, SA, maker of the glucosamine/chondroitin sulfate preparation used in the trial, funded the study.

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