Dementia Risk Increased in Seniors With Newly Diagnosed Diabetes

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Dementia Risk Increased in Seniors With Newly Diagnosed Diabetes


Seniors with newly diagnosed diabetes may have up to 16% increased risk of dementia, according to a Canadian study published online on July 27 in Diabetes Care.


The study represents the first large, populationwide study in North America to find a link between newly diagnosed diabetes and dementia in seniors.


“Our findings add to a growing understanding that diabetes is an independent risk factor for Alzheimer’s disease and vascular dementia,” commented first author Nisha Nigil Haroon, MD, PhD, of the University of Toronto, Ontario.


“Severe hypoglycemia, stroke, and vascular disease increased the risk of dementia,” she added. “Other aggravating factors include coronary events such as heart attacks, peripheral vascular disease, hypertension, and chronic kidney disease.”


Growing research supports a link between diabetes and dementia, with some studies pointing to abnormalities in insulin signaling within the central nervous system. Epidemiology studies have linked diabetes with a 1.5 times higher risk of Alzheimer’s dementia and 2.5 times higher risk of vascular dementia. Perhaps for these reasons, some experts have suggested that Alzheimer’s disease could be termed “type 3 diabetes,” according to background information in the article.


Dementia and diabetes seem to share cardiometabolic risk factors like hypertension, dyslipidemia, and obesity, which complicates the picture. Another school of thought holds that vascular complications of diabetes increase the risk for dementia.

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