Diabetes Age at Onset Affects Later Cognitive Risk

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Diabetes Age at Onset Affects Later Cognitive Risk

A new study shows that older patients who developed diabetes in midlife are more likely to have brain changes, including brain atrophy, than those who developed the disease at a later age or not at all, and that loss of brain volume is a key link between diabetes and mild cognitive impairment (MCI).

Dementia develops over a long period, during which time diabetes can have a progressively more devastating effect on the brain, said lead author Rosebud O. Roberts, MB, ChB, professor of epidemiology, Mayo Clinic, Rochester, Minnesota.

“In the absence of a cure for dementia, our findings emphasize the importance of prevention and control of type 2 diabetes as a means to reducing the burden of dementia due to Alzheimer’s or vascular dementia,” Dr. Roberts told Medscape Medical News.

The study was published online March 19 in Neurology.

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