Do you have an inherited risk for cholesterol woes? (Roizon Article)

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Do you have an inherited risk for cholesterol woes?

By Michael Roizen, M.D. on 

Genetic screening when used in combo with clinical criteria, such as your LDL cholesterol level (or, even better, your apolipoprotein B level) and/or that a family member had a heart attack at a young age, it can alert you to an inherited trait that causes extremely elevated levels of lousy LDL cholesterol, called familial hypercholesterolemia.

A recent study reveals that if health screenings were combined with genetic testing, more than 1 million Americans with an increased inherited risk could be ID’d.

It appears that one of every 1,000 U.S. adults has one gene for familial hypercholesterolemia. Those folks are, on average, at risk for a heart attack at age 50 (men) and age 60 (women). That compares to age 66 for men and age 72 for women without the predisposing gene. If you happen to have two genes for the disorder? Cholesterol and cardiovascular problems start earlier — and so does heart disease.

Unfortunately, there’s no national screening program to identify who’s at risk. So it’s up to you. If you’re 16 or older, get a test for your level of apolipoprotein B and cholesterol. Find out if anyone related to you has had a heart attack before age 60. If that’s the case and you have elevated apolipoprotein B and/or LDL, talk to your doctor about lifestyle and medication steps to save your life.

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