Even Short-term Weight Loss During Lifetime = Heart Health
Weight loss at any adult age — even if it is not maintained — is worthwhile because it may confer long-term cardiovascular health benefits, according to a unique, 60-year epidemiological study.
The newly reported research examined the effect of lifelong patterns of weight change — alterations in body mass index (BMI) — on cardiovascular risk factors and carotid intima media thickness (cIMT) at age 60 to 64.
The earlier an adult gained fat, the worse the cardiovascular disease risk profile: higher prevalence of diabetes, increased systolic blood pressure, greater cIMT, higher leptin levels, and decreased adiponectin levels.
However, people who lost enough weight in their 30s, 40s, 50s, or 60s to drop a BMI category (ie, if they went from obese to overweight or from overweight to normal weight) — even if they regained the weight — had a mean cIMT in later life that was 0.034 mm lower than individuals who were always overweight or obese in adulthood.
This difference would predict a roughly 9% lower rate for both stroke and myocardial infarction (MI), the authors say.
Lancet Diabetes Endocrinol . Published online May 21, 2014. Summary, Extract
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