Knee OA: Corticosteroid Shot Does Not Boost Exercise Benefit

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Knee OA: Corticosteroid Shot Does Not Boost Exercise Benefit

Adding an intra-articular injection of 40 mg corticosteroid before exercise in patients with painful knee osteoarthritis (OA) provided no extra benefit, results from a new randomized trial show.
Exercise has been shown to provide relief of knee OA symptoms, as have intra-articular injections, but no studies to date have evaluated the two treatments in combination.
Of the 50 patients who were assigned to each of the two trial groups, 45 in the corticosteroid group and 44 in the placebo group completed the study, researchers report in an article published online March 30 in JAMA Internal Medicine.
“Our findings should be considered in therapeutic decision making. Intra-articular corticosteroid injection and exercise are highlighted in recommendations and guidelines,” the authors conclude. “However, our results do not support the superiority of intra-articular injection of corticosteroid compared with saline and lidocaine before an exercise intervention.”
JAMA Intern Med. Published online March 30, 2015. Abstract

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