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Mediterranean Diet Cuts Some Breast Cancer Risk by 40%
Closely following a Mediterranean diet in everyday life may significantly reduce the risk for types of breast cancer that are associated with poorer prognoses in postmenopausal women, new research indicates.
The traditional Mediterranean diet is characterized by a high intake of plant proteins, whole grains, fish, and monounsaturated fat, as well as moderate alcohol intake and low intake of refined grains, red meat, and sweets, say the study authors, led by Piet A. van den Brandt, PhD, an epidemiologist at the Maastricht University Medical Center in the Netherlands.
This diet has been repeatedly shown to be associated with decreased risk for cardiovascular diseases, but the evidence in cancer, including breast cancer, is less established, say the authors.
The mechanisms of action behind the potential beneficial effects of the Mediterranean diet on cancer risk are uncertain, say the authors.
However, they say that the effects may be attributable to high amounts of fiber, antioxidants, and vitamins; they may be mediated through biological mechanisms, such as chronic inflammation and oxidative stress and through the regulation of body weight; and they may be associated DNA oxidative damage.
The study was funded by the Wereld Kanker Onderzoek Fonds Nederland as part of the World Cancer Research Fund International grant program. The authors, Dr Toledo, and Dr Bloomfield have disclosed no relevant financial relationships.
Int J Cancer. Published online March 5, 2017. Abstract
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