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Mediterranean Diet Strongly Tied to Reduced Alzheimer’s Pathology
Adherence to a Mediterranean diet (MeDi) is linked to a reduction over time in Aβ-amyloid (Aβ) accumulation, a biomarker of cerebral Alzheimer’s disease (AD) pathology, new research suggests.
In a cohort of 77 participants in the Australian Imaging, Biomarkers, and Lifestyle (AIBL) Study of Aging, who were considered cognitively healthy at baseline yet at risk for AD, a higher baseline score for overall MeDi adherence was significantly associated with less Aβ accumulation, as shown on positron emission tomography (PET).
When assessing individual components of the MeDi, only high fruit intake was significantly linked with less accumulation of Aβ.
“What surprised me was the strength of the study findings,” lead author Stephanie R. Rainey-Smith, PhD, Center of Excellence for Alzheimer’s Disease Research and Care, Edith Cowan University, Joondalup, Australia, told Medscape Medical News.
“The take-away message is that there are things that everyone can do, like modifying one’s diet, that can help to delay the onset of Alzheimer’s,” said Rainey-Smith.
In addition, “it would be a good idea to ask your patients to follow the Mediterranean diet,” she added. “There’s an overwhelming body of evidence that suggests that it’s beneficial in many ways, not just in terms of reducing Alzheimer’s risk.”
The findings were recently published online in Translational Psychiatry.
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