One in Five With Type 2 Diabetes Nonresponsive to Exercise

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One in Five With Type 2 Diabetes Nonresponsive to Exercise

About one in five people with type 2 diabetes do not respond favorably to exercise, a new literature review finds.

Taken together, the data suggest that between 15% and 20% of patients with type 2 diabetes will not experience improvements in HbA1c, insulin sensitivity, percent body fat, or muscle mitochondrial content even with supervised exercise.

Clinically, the findings mean that a patient may be truly attempting to comply with an exercise prescription and simply not responding to it, just as some people don’t respond to weight-loss drugs, the researchers say.

The paper was published online November 20 in the Journal of Clinical Endocrinology and Metabolism by Dr Natalie A Stephens (Translational Research Institute for Metabolism and Diabetes, Florida Hospital, Orlando and Sanford Burnham Medical Research Institute, Orlando) and Dr Lauren M Sparks (Sanford Burnham Medical Research Institute).

J Clin Endocrinol and Metab. November 20, 2014. Available at: http://bit.ly/11KUBSW.

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