Oral Steroids Have Little Effect in Patients With Sciatica

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Oral Steroids Have Little Effect in Patients With Sciatica

A short course of oral prednisone slightly improves function but has no effect on acute radicular leg pain (sciatica) or subsequent need for surgery among patients with a herniated lumbar disk, according to a study published in the May 19 issue of JAMA.


Although oral steroids are commonly used as a less-invasive alternative to epidural steroid injections for lumbar radiculopathy, their efficacy has not been evaluated in appropriately powered clinical trials, write Harley Goldberg, DO, from the Kaiser Permanente Northern California Spine Care Program, San Jose, California, and colleagues.


JAMA. 2015;313:1924-1938. Abstract

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