Saliva Test for Alzheimer’s

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Saliva Test for Alzheimer’s


Canadian researchers have developed a simple saliva test for the diagnosis of Alzheimer’s disease, which they say may also be used to identify individuals at high risk of developing the condition in future.
The test is based on detecting levels of amyloid β42 (Aβ42), a peptide fraction of amyloid-β protein precursor.
In a paper published online in the Journal of Alzheimer’s Disease, the researchers, from Aurin Biotech Inc Ltd, Vancouver, British Columbia, Canada, describe studies they say show that Aβ42 is continuously being generated throughout the body and is secreted into the saliva as well as other tissues and bodily fluids.
On interventions to prevent Alzheimer’s, he said, “There are things people can do to reduce their risk, such as exercise and eating a healthy diet — however, it’s important to note that people can develop Alzheimer’s despite doing these things. Medium- or long-term use of NSAIDs may be associated with a reduced risk of developing Alzheimer’s disease, but early drugs of this type can have severe side effects and it remains to be seen whether newer forms of these drugs could be effective.”
The study was funded by Aurin Biotech. Dr McGeer is president and CEO of Aurin Biotech. Dr Knopman, Dr Fargo, and Dr Shakespeare have disclosed no relevant financial relationships.
J Alzheimers Dis. Published online October 24, 2016. Abstract

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