Smoking May Cut Life Expectancy in ALS

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Smoking May Cut Life Expectancy in ALS


A new study shows smoking is linked to reduced survival in patients diagnosed with amyotrophic lateral sclerosis (ALS).
Researchers found that being a current smoker negatively affects ALS prognosis, independent of age, sex, and other known modifiers, including chronic obstructive pulmonary disease (COPD) and genetic status.
The new research makes at least two important points, said study author Adriano Chiò, professor of neurology, University of Torino, Italy. The first is that it suggests that smoking not only is a risk factor for development of ALS but also modifies the prognosis of the disease, probably because it affects the genome.
“The second point is that the smoking effect is not related to the respiratory function of the patient,” said Dr Chiò. “This is very important because we also found that COPD is another negative prognostic factor for ALS.”
The study was published online September 21 in the Journal of Neurology Neurosurgery & Psychiatry.

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