Synthetic Cannabis-like Drug Effective for Sleep Apnea

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Synthetic Cannabis-like Drug Effective for Sleep Apnea

Dronabinol, a synthetic form of the cannabis compound   tetrahydrocannabinol (THC), shows efficacy in the treatment of obstructive sleep apnea (OSA), possibly representing a first pharmacologic approach to the tough-to-treat but potentially serious condition.
“These findings support the therapeutic potential of cannabinoids in patients with obstructive sleep apnea,” the authors, led by Phyllis Zee, MD, the Benjamin and Virginia T. Boshes Professor of Neurology at Northwestern University Feinberg School of Medicine and director of the Northwestern Medicine Sleep Disorders Center, Chicago, Illinois, write.
“In comparison to placebo, dronabinol was associated with lower apnea/hypopnea index (AHI), improved subjective sleepiness and greater overall treatment satisfaction,” they add.
The study was published online in Sleep.

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